Bootcamp: Experimental Approaches in Genetics
GENETIC 390QC
Subject & Catalog Number
Course Information
Description
The goal of this course is to provide you with a hands-on survey of major topics and themes in genetic and genomic analysis, as well as exposure to numerous experimental techniques and model organisms. Over the course of nine days, you will spend each day in a new lab across Longwood, learning directly from faculty, postdocs, and senior graduate students. You will gain experience using genetic approaches to address biologically relevant questions in a variety of experimental systems, including bacteria, yeast, nematodes, zebrafish, mice, human cells, and cancer models. You will also learn about clinical cytogenetics and protein structure prediction using AlphaFold. The course will combine short lectures, hands-on laboratory activities, and facility visits that emphasize experimental methods, hypothesis generation and testing, and data analysis.
You will be graded on a pass/fail basis. To receive credit for this course, you are expected to attend and arrive prepared for every session, complete daily evaluations of course activities as well as a final overall course evaluation, and give a short research-idea presentation at the end of the course
The participating labs are listed within the course notes.
Course Notes
Priority will be given to first-year graduate students.
Class Notes
Meeting Location: Research labs across the Longwood Campus
The participating labs are as follows:
- van Opijnen Lab - Bacterial genetics
- Moazed Lab - Yeast genetics
- Kennedy Lab - Nematode genetics
- Harris Lab - Zebrafish genetics
Sinclair Lab - Mouse genetics and aging
- Morton Lab - Human cytogenetics
- Naxerova Lab - Cancer genetics
Walter Lab - Frog genetics and Protein structure prediction with AlphaFold
Recommended Prep
Genetics 201 or permission from the Course director/Curriculum Fellow
Available for Harvard Cross Registration