Genuinely Hard Problems in Science
FYSEMR 58C
Subject & Catalog Number
Course Information
Description
This seminar explores some of science's most significant unsolved challenges: Genuinely Hard Problems (GHPs) that have stumped researchers despite their best efforts. To solve these problems, technical execution is not enough—we need true conceptual breakthroughs. Examples include reconciling quantum mechanics with gravity or finding the biological mechanisms that cause mental illness.
A key part of the seminar is identifying a GHP that deeply interests you. Each week will feature Harvard faculty whose research is related to these GHPs. Maybe it's the origin of life, dark matter and the structure of the universe, or cracking the code of human aging. They will make a pitch to serve as your academic mentor, and together, you'll plan an undergraduate curriculum focused on building the skills and knowledge you'd need to tackle your chosen GHP. You'll also study historical cases where seemingly impossible problems were solved, often by young researchers with fresh perspectives.
By the end of the seminar, you'll have a clearer picture of the scientific landscape and where you might fit into it. We hope that some of you will embark on a tailored academic journey here at Harvard, aimed at equipping you to address some of science's most profound mysteries. No prior scientific expertise is required—just deep curiosity, openness to failure, and willingness to grapple with big ideas.
Class Notes
First-Year Seminars are available only to first-year students. You may apply to both Fall 2026 and Spring 2027 First-Year Seminars via the FYS lottery between July 6 and August 6, 2026 at 11:59PM-midnight.
You may apply to as many seminars each term as you would like, but we recommend you apply to at least six in fall and three in spring.
As part of your application, you must provide a brief statement on why you are interested in each seminar. You will be notified of lottery results for both fall and spring seminars at 5 pm on August 11. If you are unsuccessful in the lottery, you may still join any seminar with open seats. A list of open seminars and instructions on next steps will be available on the First-Year Seminar Program website August 11 at 12 Noon.
Not Available for Cross Registration
