The Chemistry and Biology of Therapeutics
CHEM 110
Subject & Catalog Number
Course Information
Description
This course will cover the chemical and biological principles that govern small molecule therapeutics. We will discuss small molecule conformational analysis, chemical forces that drive small molecule-protein interactions, and small molecule binding to proteins to affect disease states. We will also discuss how protein targets are identified and the frontiers of modern small molecule therapeutics. Protein targets include, but are not limited to kinases, proteases, GTPases, scaffolding proteins, epigenetic modifiers, metabolic enzymes and transcription factors. This course will teach students how to use modern computer modeling applications to perform structure-based design of small molecule ligands.
Course Notes
Course Requirements: Completion of Chem 27, Chem 30, or prior instructor approval.
Available for Harvard Cross Registration
NOTE: This course requires additional sections; you will be prompted to choose secondary components during the Add to Cart process
