Biology of the Cancer Cell: From Molecular Mechanisms to Therapeutic Implications

CELLBIO 212 Subject & Catalog Number

Description

This semester-long course will take you on a molecular-level exploration to examine the basis of human cancer - from a deep dive on genetic aberrations in a cancer cell, through signaling pathways, to big picture cellular and organismal perspectives on cancer. Some of the main concepts we will cover include cancer genetics and epigenetics, tumor suppressor genes and oncogenes, signal transduction, DNA damage and repair, angiogenesis, metastasis and invasion, apoptosis, cancer stem cells, and tumor immunology and immunotherapy. Faculty joining us this Spring are experts in the various fields and will provide you with an integrated perspective on past, current, and future approaches in cancer biology research. Many of our faculty are also clinical oncologists and hematologists, offering an insight into how molecular advances are impacting patient care now and are likely to do so in the future. After each part of the course, you will participate in Student Workshops, where you will dissect and learn about the major components of a research proposal and how to successfully write one. You will also engage in an iterative writing and evaluation process with your peers while practicing giving feedback and critique.

COURSE OBJECTIVES
* Understand foundational discoveries that led to major concepts in the field
* Describe the molecular basis of cancer formation
* Identify big open questions in the research areas around these topics
* Synthesize and implement content knowledge while practicing writing skills
* Identify the main components of a research proposal
* Write a research proposal draft
* Practice your peer evaluation and critique skills

Course Notes

Given alternate years with Cell Biology 211.

Recommended Prep

Advanced biochemistry, molecular genetics, and cell biology.